Relief from Depression Symptoms Is Possible
At New Directions Mental Health, we’re proud to offer Spravato®, an esketamine-based nasal spray known for offering relief from depression symptoms in as little as a few hours. It works by quickly shifting brain chemistry, reducing symptoms such as low mood, hopelessness, and disinterest in things that used to bring joy. Complete our Spravato® form below to see whether this powerful treatment might be a good option for you or a loved one.
Spravato® is administered in our clinics under close supervision from a licensed healthcare professional. It has proven to be highly effective for many people who haven’t found relief from conventional antidepressants or talk therapy alone, offering hope to people who have felt stuck in their depression. While it isn’t a cure, Spravato® can provide new relief from depression symptoms and support a better overall quality of life. It’s often covered by insurance, and may fall under your medical or pharmacy benefit, depending on your specific plan.
How Spravato® Treatment Works at New Directions Mental Health

Our Spravato® treatment process generally follows these steps:
- Initial screening: We begin with an evaluation to confirm whether Spravato® is an appropriate part of your depression treatment plan.
- A dedicated education session: Before treatment starts, our clinical team makes sure you understand exactly how Spravato® works.
- On-site administration: A qualified healthcare professional delivers the medication in our office, and you’ll be monitored for two hours after every dose to watch for any negative reactions.
- Consistent appointments: Depending on what you and your care team decide, you’ll schedule regular Spravato® doses for at least the first several weeks of treatment, updating your providers on your progress.
- Ongoing therapeutic care: Our team will partner with you to build strategies for managing depression symptoms over time. We highly recommend that everyone getting Spravato® treatment also see a therapist to treat the depression from multiple angles.
We’re committed to making your experience with Spravato®, and any other depression treatment you receive, as supportive as possible. We know depression can make it hard to feel a sense of control over your life, so our clinicians will walk alongside you, starting from your very first screening appointment. With consistent, thoughtful care, we believe lasting improvement is achievable for every one of our clients.
Find out if Spravato® could help relieve your depression symptoms.
Spravato® Is One Aspect of a Comprehensive Depression Treatment Plan
We typically encourage that Spravato® be added to other depression treatments, including therapy and often another oral antidepressant. Spravato® encourages new plasticity and communication networks in the brain, often leading to new insights in therapy. People who start Spravato® often find that they have an easier time discovering new insights, implementing coping skills, and breaking patterns, even if they were in therapy for years beforehand with limited results.
Start Spravato® Treatment at New Directions Mental Health
If traditional depression treatments haven’t given you the relief you were hoping for, New Directions Mental Health offers Spravato® as part of a broader treatment approach that includes therapy, psychiatric medication management, and other supports. Our teams pride themselves on offering comprehensive, empathetic treatment to our neighbors in Pittsburgh, Fox Chapel, Washington, and across Southwestern Pennsylvania.
Call 724.374.7414 to learn more, or complete our Spravato® form to see if this treatment could help you or someone in your life.
Frequently Asked Questions About Spravato®
Is Spravato® safe?
Yes, Spravato® is incredibly safe for most clients, and usually comes with few side effects. We review your medical history thoroughly before you start, and monitor closely throughout treatment for any adverse reactions.
Does Spravato® hurt?
As a nasal spray, some mild discomfort in the nasal passages is possible during administration. Our team can offer tips to help make each session more comfortable.
How do I know if Spravato® is right for me?
Spravato® is often a good fit for people managing difficult-to-treat depression who haven’t found sufficient relief through other, more traditional treatment routes. If you think Spravato® could be right for you, fill out our intro form to have a conversation with one of our providers about your eligibility.
Is a referral necessary for getting Spravato®?
No referral is needed. Our clinical team can assess your symptoms directly and help determine whether Spravato® is right for you.
When can I expect to see results?
Many people notice symptom improvement within a few days of beginning Spravato® treatment, though timelines vary from person to person. We build your treatment plan around your specific needs and can change the pace or add other supports to your treatment plan if necessary.
Does Spravato® actually work?
Clinical trials of Spravato® have shown strong results. After 30 days, 62% of participants reported improved social functioning and 53% saw a better overall quality of life. Additionally, 41% experienced an increased ability to work, 37% found it easier to meet basic needs, and 34% reported better overall health.¹
Does insurance typically cover Spravato®?
Many insurance plans provide coverage for Spravato® if other depression treatments haven’t worked. Co-pay assistance and payment plans may also be available. Our team can help you understand your specific coverage and what you can expect to pay before you start treatment.