Managing treatment-resistant depression (TRD) can be challenging, as many still experience significant symptoms despite trying different medications and therapies. This condition deeply affects daily life, highlighting the need for innovative approaches and support.
In recent years, two treatment options have emerged as potential solutions for TRD—transcranial magnetic stimulation (TMS) therapy and Spravato® nasal spray. While both treatments target the same condition, their approach, administration, and effectiveness differ. At select New Directions Mental Health locations, we offer Spravato® and TMS therapy services tailored to your needs. Call 724.374.7414, and our team will help connect you with a provider to discuss which option may be best for you.
Types of Treatment for Treatment-Resistant Depression
Treatment-resistant depression is a type of depression that doesn’t get better with regular antidepressant medicines or therapy. This can present unique challenges for both clients and doctors because it needs a special and different approach. TRD happens when someone hasn’t improved much after trying two or more different antidepressants in the right doses.
Here are some treatments that might help:
- Transcranial magnetic stimulation – A procedure using magnets to stimulate brain cells without surgery.
- Spravato® – A quick-acting nasal spray that is approved by the FDA and can help some people feel better fast.
- Psychotherapy – Includes different types of talk therapy to help people change their thoughts, feelings, and behaviors.
- Medications – Even if many drugs don’t work, changing dosages, adding mood stabilizers, or trying different drug combinations could help.
Doctors should discuss each treatment to find the best and kindest care for each person’s specific needs. TRD can be frustrating to manage, but it’s not impossible.
TMS vs. Spravato®: Understanding the Difference
Transcranial Magnetic Stimulation Therapy
TMS therapy is a non-invasive and FDA-approved treatment that uses magnetic pulses to stimulate specific areas of the brain associated with mood regulation. The pulses are delivered through a coil placed on the individual’s head, targeting the prefrontal cortex.
The goal of TMS therapy is to improve symptoms of depression by increasing activity in these targeted brain regions, which are often underactive in individuals with TRD. The procedure typically takes around 30 minutes and requires daily sessions for several weeks.
Spravato® Treatment
Spravato®, also known as esketamine, is an FDA-approved nasal spray medication that targets a different area of the brain than TMS therapy. It works by activating a specific type of receptor in the brain that is involved in regulating mood.
Unlike traditional antidepressants, which can take weeks to show results, Spravato® has been shown to have relatively fast-acting effects within hours or days. However, it also requires regular administration and may cause side effects such as dissociation or sedation.
Choosing the Right Treatment for You
Different individuals may respond differently to TMS therapy and Spravato®, depending on their unique needs and preferences. Some factors to consider when choosing between these treatments include:
- Severity of depression symptoms
- Previous treatment history
- Medications currently used
- Potential side effects
Benefits and Possible Side Effects of TMS vs. Spravato®
TMS therapy is a non-invasive option with minimal side effects, ideal for those who prefer drug-free treatments. It focuses on brain stimulation and may have fewer lasting side effects than medications. Some of TMS therapy’s side effects may include mild discomfort at the treatment site, headaches, or muscle twitching.
Spravato® is known for its fast action, providing quick relief from depressive symptoms, which can be crucial for clients needing immediate assistance. However, its use may come with side effects such as dizziness, sedation, or feelings of dissociation.
Ultimately, it’s important to discuss these options with a mental health professional who can evaluate your specific situation and recommend the most appropriate treatment plan for you. At New Directions Mental Health, our team of compassionate providers will work closely with you to understand your needs and provide personalized care.
Reach Out to New Directions Mental Health for Guidance in Choosing TRD Treatment
Getting the treatment that you need for TRD is possible. At New Directions Mental Health, we offer TMS therapy and Spravato® services to help our clients find relief from depression symptoms. Call 724.374.7414 to learn more about mental health treatment options at one of our locations near you.
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